Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.77 |
| ▸ | HPGD | P15428 | 7/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | HTT | P42858 | 2/20 | 0.77 |
| ▸ | BRD4 | O60885 | 1/20 | 0.77 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913227 | 0.91 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL2849523 | 0.90 | DRD3 (0.76) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL7824016 | 0.90 | DRD3 (0.63) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10915571 | 0.90 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Asparagine SCHEMBL11012428 | 0.89 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| SCHEMBL10913654 | 0.89 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Glutamic Acid SCHEMBL11011088 | 0.89 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Gluconic Acid SCHEMBL11013327 | 0.88 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Hydrochloric Acid SCHEMBL10656732 | 0.88 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Glucuronic Acid SCHEMBL11012131 | 0.87 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3263145-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2021-01-20 | — | — | EP | claimed |
| EP-2391632-B1 | BACTERIOSTATIC CATHETER LOCK CONTAINING GLYCEROL | TELEFLEX MEDICAL INC (US) | 2017-11-15 | — | — | EP | claimed |
| EP-1998825-B1 | ANTIMICROBIAL COMPOSITIONS AND METHODS FOR LOCKING CATHETERS | BECTON DICKINSON CO (US) | 2017-10-18 | — | — | EP | claimed |
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | claimed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | claimed |
| EP-1244434-A2 | USE OF CHEMOTHERAPEUTIC AGENTS | Schulz, Hans-Herrmann (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001045679-A2 | USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT | SCHULZ HANS HERRMANN (DE) | 2001-06-28 | — | — | WO | claimed |
| EP-0300735-B1 | ANTIMICROBIAL PHARMACEUTICAL COMPOSITION | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-10-14 | — | — | EP | claimed |
| EP-0155006-B1 | COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FARMADES S.p.A. (IT) | 1990-10-24 | — | — | EP | claimed |
| EP-0036138-B2 | Composition of matter for topical application comprising a bio-affecting agent and N,N-diethyl-m-toluamide | MERCK & CO. INC. (US) | 1989-10-25 | — | — | EP | claimed |
| EP-0083032-B1 | RECTALLY ADMINISTRABLE SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT | MERCK & CO. INC. (US) | 1989-09-20 | — | — | EP | claimed |
| EP-0210513-A1 | Preparations for the treatment of mycoplasmoses and bacterial infections in poultry | BAYER AG (DE) | 1987-02-04 | — | — | EP | claimed |
| EP-0049593-B1 | 1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-7-(1-PIPERAZINYL)-3-QUINOLINE CARBOXYLIC ACID AND METAL SALTS THEREOF USEFUL IN BURN THERAPY | Fox, Charles l., Jr. (US) | 1986-08-27 | — | — | EP | claimed |
| EP-0084011-B1 | QUINOLINE CARBOXYLIC ACID COMPLEXES WITH GUANIDINIUM CARBONATE AND GUANIDINE | MERCK & CO. INC. (US) | 1986-03-26 | — | — | EP | claimed |
| EP-0067666-B1 | SALTS OF ANTIMICROBIAL NAPHTHYRIDINE AND QUINOLINE COMPOUNDS AND THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1985-10-30 | — | — | EP | claimed |
| EP-1682144-B1 | PHARMACEUTICAL FORMULATIONS CONTAINING FLAVOURING SUBSTANCES WITH IMPROVED PHARMACEUTICAL PROPERTIES | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-13 | — | — | EP | disclosed |
| EP-2080515-A1 | Pharmaceutical formulations containing flavouring substances with improved pharmaceutical properties | Bayer Animal Health GmbH (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-0113093-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(alkyl-1-piperazinyl)-3-quinoline-carboxylic acids, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0113092-A1 | 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(oxoalkyl)-1-piperazinyl)-3-quinoline-carboxylic acids and their derivatives, process for their preparation and antibacterial agents containing them | BAYER AG (DE) | 1984-07-11 | — | — | EP | disclosed |
| EP-0049593-A1 | 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinoline carboxylic acid and metal salts thereof useful in burn therapy | Fox, Charles l., Jr. (US) | 1982-04-14 | — | — | EP | disclosed |