Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | RAD52 | P43351 | 1/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7809358 | 0.92 | ALDH1A1 (0.76) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7824016 | 0.92 | DRD3 (0.63) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2858133 | 0.90 | KDM4E (0.77) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10913829 | 0.89 | DRD3 (0.68) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10359339 | 0.86 | HSD17B10 (0.65) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| Pefloxacin SCHEMBL34292 | 0.86 | DRD3 (1.00) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| Pefloxacin SCHEMBL29351730 | 0.86 | DRD3 (1.00) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| Pefloxacin SCHEMBL28251251 | 0.86 | DRD3 (1.00) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| Pefloxacin SCHEMBL10911017 | 0.85 | DRD3 (0.98) | DRD3KDM4EALDH1A1MEN1KMT2A | |
| Pefloxacin SCHEMBL9800276 | 0.85 | DRD3 (0.98) | DRD3KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | claimed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | claimed |
| EP-1244434-A2 | USE OF CHEMOTHERAPEUTIC AGENTS | Schulz, Hans-Herrmann (DE) | 2002-10-02 | — | — | EP | claimed |
| WO-2001045679-A2 | USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT | SCHULZ HANS HERRMANN (DE) | 2001-06-28 | — | — | WO | claimed |
| EP-0210513-A1 | Preparations for the treatment of mycoplasmoses and bacterial infections in poultry | BAYER AG (DE) | 1987-02-04 | — | — | EP | claimed |
| EP-1682144-B1 | PHARMACEUTICAL FORMULATIONS CONTAINING FLAVOURING SUBSTANCES WITH IMPROVED PHARMACEUTICAL PROPERTIES | BAYER ANIMAL HEALTH GMBH (DE) | 2010-01-13 | — | — | EP | disclosed |
| EP-2080515-A1 | Pharmaceutical formulations containing flavouring substances with improved pharmaceutical properties | Bayer Animal Health GmbH (DE) | 2009-07-22 | — | — | EP | disclosed |
| EP-1408034-B1 | Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents | SCHULZ & SCHLIMBACH GBR (DE) | 2007-08-08 | — | — | EP | disclosed |
| EP-1682144-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING FLAVOURING SUBSTANCES WITH IMPROVED PHARMACEUTICAL PROPERTIES | Bayer HealthCare AG (DE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005044271-A1 | PHARMACEUTICAL FORMULATIONS CONTAINING FLAVOURING SUBSTANCES WITH IMPROVED PHARMACEUTICAL PROPERTIES | BAYER HEALTHCARE AG (DE) | 2005-05-19 | — | — | WO | disclosed |
| EP-1408034-A1 | Use of Quinoline derivatives as antibacterial agents | Schulz & Schlimbach GbR (DE) | 2004-04-14 | — | — | EP | disclosed |
| EP-1244434-A2 | USE OF CHEMOTHERAPEUTIC AGENTS | Schulz, Hans-Herrmann (DE) | 2002-10-02 | — | — | EP | disclosed |
| EP-0828715-B1 | N-OXIDES AS ANTIBACTERIAL AGENTS | BAYER AG (DE) | 2001-08-16 | — | — | EP | disclosed |
| WO-2001045679-A2 | USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT | SCHULZ HANS HERRMANN (DE) | 2001-06-28 | — | — | WO | disclosed |
| EP-0270904-A2 | Process for the preparation of quinoloncarboxylate esters | BAYER AG (DE) | 1988-06-15 | — | — | EP | disclosed |
| EP-0210513-A1 | Preparations for the treatment of mycoplasmoses and bacterial infections in poultry | BAYER AG (DE) | 1987-02-04 | — | — | EP | disclosed |
| EP-0209000-A2 | Embonates of quinoline-carboxylic acids and their derivatives | BAYER AG (DE) | 1987-01-21 | — | — | EP | disclosed |
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |