Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857804 | 0.96 | KEAP1 (0.32) | KEAP1NFE2L2 | |
| SCHEMBL2861725 | 0.91 | GRM2 (0.31) | — | |
| SCHEMBL28004680 | 0.91 | KEAP1 (0.37) | KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL28004203 | 0.89 | KEAP1 (0.36) | KEAP1NFE2L2 | |
| SCHEMBL28315722 | 0.88 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL21269988 | 0.88 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL21269474 | 0.88 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL21269676 | 0.88 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL28314487 | 0.88 | KEAP1 (0.35) | KEAP1NFE2L2 | |
| SCHEMBL28315925 | 0.88 | KEAP1 (0.35) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822366-B2 | Solid titanium catalyst component, catalyst for olefin polymerization and process for polymerizing olefin | MITSUI CHEMICALS, INC. (JP) | 2014-09-02 | — | — | US | disclosed |
| EP-2206731-B1 | SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD | MITSUI CHEMICALS INC (JP) | 2013-08-28 | — | — | EP | disclosed |
| US-20100227991-A1 | SOLID TITANIUM CATALYST COMPONENT, CATALIST FOR OLEFIN POLYMERIZATION AND PROCESS FOR POLYMERIZING OLEFIN | MITSUI CHEMICALS, INC. (JP) | 2010-09-09 | — | — | US | disclosed |
| EP-2206731-A1 | SOLID TITANIUM CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, AND OLEFIN POLYMERIZATION METHOD | Mitsui Chemicals, Inc. (JP) | 2010-07-14 | — | — | EP | disclosed |