Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29039971 | 1.00 | ACE (0.54) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL29039962 | 0.87 | KLK5 (0.49) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL215178 | 0.84 | ACE (0.56) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL29613833 | 0.84 | ACE (0.56) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL268002 | 0.84 | ACE (0.56) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL215179 | 0.84 | ACE (0.56) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL29573143 | 0.84 | ACE (0.56) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL23963116 | 0.84 | ITGB3 (0.53) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL31667889 | 0.82 | ACE (0.49) | ACEITGB3ITGA2BPTPN1PPARA | |
| SCHEMBL15662715 | 0.82 | ACE (0.50) | ACEITGB3ITGA2BPTPN1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709301-B | Pyrazole derivative or pharmacologically acceptable salt thereof | 橘生药品工业株式会社 | 2021-06-22 | — | — | CN | disclosed |