Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PRNP | P04156 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28586649 | 0.93 | RXFP1 (0.43) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28585668 | 0.86 | RXFP1 (0.41) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28594412 | 0.86 | RXFP1 (0.40) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL20312984 | 0.85 | RXFP1 (0.44) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28579298 | 0.84 | RXFP1 (0.40) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28594400 | 0.84 | RXFP1 (0.42) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL27955062 | 0.82 | ESR2 (0.50) | RXFP1CYP1A2CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL28275469 | 0.81 | PGR (0.42) | RXFP1CYP1A2MEN1KMT2AHTT | |
| SCHEMBL28583244 | 0.81 | KMT2A (0.44) | RXFP1CYP1A2ESR2PRNPHIF1A | |
| SCHEMBL19757717 | 0.81 | ESR2 (0.41) | RXFP1CYP1A2ESR2PRNPHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400438-B | Synthesis method of 9, 10-disubstituted phenanthrene compound | 西北大学 | 2021-07-02 | — | — | CN | disclosed |