Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FER | P16591 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MARK3 | P27448 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.39 |
| ▸ | STK3 | Q13188 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076432 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1DCLK1PRKD3MAP4K4 | |
| SCHEMBL17343994 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPK1DCLK1PRKD3MAP4K4 | |
| SCHEMBL28594412 | 0.85 | RXFP1 (0.40) | ALDH1A1MAPK1TNKS2DCLK1PRKD3 | |
| SCHEMBL21636027 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1DCLK1PRKD3MAP4K4 | |
| SCHEMBL21445710 | 0.84 | ALDH1A1 (0.52) | ALDH1A1MAPK1DCLK1PRKD3MAP4K4 | |
| SCHEMBL28583244 | 0.83 | KMT2A (0.44) | ALDH1A1MAPK1DCLK1PRKD3MAP4K4 | |
| SCHEMBL19757717 | 0.83 | ESR2 (0.41) | ALDH1A1MAPK1DCLK1PRKD3MAP4K4 | |
| SCHEMBL28579298 | 0.83 | RXFP1 (0.40) | ALDH1A1MAPK1TNKS2DCLK1PRKD3 | |
| SCHEMBL12791358 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPK1TNKS2DCLK1PRKD3 | |
| SCHEMBL17343997 | 0.81 | ALDH1A1 (0.65) | ALDH1A1MAPK1TNKS2RXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109400438-B | Synthesis method of 9, 10-disubstituted phenanthrene compound | 西北大学 | 2021-07-02 | — | — | CN | disclosed |