Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 7/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822422 | 0.90 | ALDH1A1 (0.44) | PPARGALDH1A1CYP3A4CYP2C9HPGD | |
| SCHEMBL28579613 | 0.90 | KMT2A (0.46) | PPARGALDH1A1CYP3A4CYP2C9HPGD | |
| SCHEMBL28916291 | 0.86 | PPARG (0.49) | PPARGALDH1A1CYP3A4CYP2C9HPGD | |
| SCHEMBL21822515 | 0.83 | RXFP1 (0.45) | PPARGALDH1A1CYP3A4CYP2C9HPGD | |
| SCHEMBL25016097 | 0.82 | F2 (0.42) | PPARGALDH1A1KMT2APOLB | |
| SCHEMBL25017313 | 0.79 | PLAU (0.43) | ALDH1A1HPGDKMT2A | |
| SCHEMBL25017838 | 0.76 | PLAU (0.44) | ALDH1A1 | |
| SCHEMBL25015686 | 0.75 | PLAU (0.45) | ALDH1A1 | |
| SCHEMBL25017840 | 0.71 | NPC1 (0.46) | ALDH1A1KMT2APOLBTDP1LMNA | |
| SCHEMBL25015689 | 0.71 | F10 (0.49) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |