Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.48 |
| ▸ | FLT1 | P17948 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27677910 | 0.82 | KDM4E (0.65) | KDM4EPOLBSMN1; SMN2NR4A2TDP1 | |
| SCHEMBL5705595 | 0.81 | NR4A2 (0.67) | KDM4ESMN1; SMN2NR4A2MAPTRAB9A | |
| SCHEMBL10596909 | 0.81 | KDM4E (0.49) | KDM4EPOLBCDK1CDK2SMN1; SMN2 | |
| SCHEMBL6487558 | 0.79 | KDM4E (0.63) | KDM4ESMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8504135 | 0.79 | NR4A2 (0.68) | KDM4EPOLBSMN1; SMN2NR4A2TDP1 | |
| SCHEMBL29955046 | 0.78 | KDM4E (0.66) | KDM4EPOLBNR4A2TDP1MAPT | |
| SCHEMBL2339411 | 0.78 | KDM4E (0.66) | KDM4EPOLBNR4A2TDP1MAPT | |
| SCHEMBL13062894 | 0.77 | KDM4E (0.55) | KDM4ESMN1; SMN2NR4A2TDP1MAPT | |
| SCHEMBL2284247 | 0.77 | KDM4E (0.69) | KDM4EPOLBSMN1; SMN2TDP1MAPT | |
| SCHEMBL26963262 | 0.77 | KDM4E (0.55) | KDM4ENR4A2TDP1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188045-A1 | METHOD FOR CATALYTIC PREPARATION OF PYRANO[2,3-B]INDOLE-2-ONE COMPOUND | 苏州大学 | 2022-09-15 | — | — | WO | disclosed |
| CN-112961166-B | Catalytic preparation of pyrano [2,3-b]Process for preparing indol-2-one compounds | 苏州大学 | 2022-02-25 | — | — | CN | disclosed |
| CN-112961166-A | Catalytic preparation of pyrano [2,3-b]Process for preparing indol-2-one compounds | 苏州大学 | 2021-06-15 | — | — | CN | disclosed |