Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL168064 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL1237975 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL165537 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL167865 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL584656 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL167222 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL17646227 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL425589 | 0.96 | GPR84 (0.60) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5740376 | 0.95 | GPR84 (0.57) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL6910867 | 0.92 | GPR84 (0.55) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482915-B1 | THERAPEUTIC SYSTEM FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | JAGOTEC AG (CH) | 2010-01-13 | — | — | EP | disclosed |
| US-20050163845-A1 | tablet comprising a nucleus coated with polymeric film, insoluble and impermeable to water including laser cut incisions delimiting an area having exactly programmable and defined dimensions and geometric shape; in biological fluids, the portion of film inside incision(s) detaches and releases drug | JAGOTEC AG (CH) | 2005-07-28 | — | — | US | disclosed |
| US-20050095295-A1 | Therapeutic system for the controlled release of active ingredients | JAGOTEC AG (CH) | 2005-05-05 | — | — | US | disclosed |
| EP-1482915-A1 | THERAPEUTIC SYSTEM FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | JAGOTEC AG (CH) | 2004-12-08 | — | — | EP | disclosed |
| EP-1482913-A1 | A SYSTEM FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | JAGOTEC AG (CH) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003075894-A1 | A SYSTEM FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | JAGOTEC AG (CH) | 2003-09-18 | — | — | WO | disclosed |
| WO-2003075897-A1 | THERAPEUTIC SYSTEM FOR THE CONTROLLED RELEASE OF ACTIVE INGREDIENTS | JAGOTEC AG (CH) | 2003-09-18 | — | — | WO | disclosed |