Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL223115 | 1.00 | SLC34A1 (0.73) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL28373362 | 0.95 | SLC34A1 (0.67) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL30341783 | 0.95 | SLC34A1 (0.67) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL28498921 | 0.95 | SLC34A1 (0.67) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL23091295 | 0.95 | SLC34A1 (0.67) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL23294021 | 0.95 | SLC34A1 (0.67) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL9307266 | 0.95 | SLC34A1 (0.67) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL5608739 | 0.95 | SLC34A1 (0.82) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL532270 | 0.95 | SLC34A1 (0.82) | SLC34A1KDM4ECYP2C19KMT2ALMNA | |
| Phosphoric Acid SCHEMBL4332135 | 0.95 | SLC34A1 (0.82) | SLC34A1KDM4ECYP2C19KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134771-A1 | PHARMACEUTICAL COMPOSITION OF ANTI-CTLA-4 ANTIBODY AND USE THEREOF | 上海君实生物医药科技股份有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-115417746-A | Process and apparatus for the synthesis of alcohols from olefins | 上海华谊（集团）公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-110770256-B | AXL-targeted antibody and antibody-drug conjugate, and preparation methods and applications thereof | 复旦大学 | 2022-08-19 | — | — | CN | disclosed |
| CN-114874083-A | Olefin hydroformylation method and system | 上海华谊（集团）公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111471668-B | Nitrilase mutant and application thereof in preparation of 1-cyanocyclohexylacetic acid | 浙江工业大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-111172140-B | Nitrilase mutant and application thereof in preparation of anti-epileptic drug intermediate | 浙江工业大学 | 2022-04-19 | — | — | CN | disclosed |
| CN-108998432-B | Acid phosphatase gene and application | 中国农业科学院农业资源与农业区划研究所 | 2022-04-12 | — | — | CN | disclosed |
| CN-109234251-B | Protein and application of nucleic acid molecule for coding protein in preparation of phosphohydrolase | 中国农业科学院农业资源与农业区划研究所 | 2022-04-12 | — | — | CN | disclosed |
| CN-114317498-A | Alpha-transglucosidase mutant and application thereof | 山东恒仁工贸有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-114306633-A | Preparation method of disubstituted bridging antibody coupling drug | 迈威(上海)生物科技股份有限公司 | 2022-04-12 | — | — | CN | disclosed |
| WO-1997031628-A1 | PEPTIDOMIMETICS FOR THE TREATMENT OF HIV INFECTION | INNAPHARMA, INC. (US) | 1997-09-04 | — | — | WO | disclosed |
| US-5650062-A | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1997-07-22 | — | — | US | disclosed |
| US-5582697-A | Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0672414-A2 | Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen | Senju Pharmaceutical Co., Ltd. (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5409583-A | Method for measuring concentrations of substrates in a sample liquid by using a biosensor | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5308836-A | Mixing with carboxylic acid or salt | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0590661-A1 | A method for measuring concentrations of substrates in a sample liquid by using a biosensor | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| EP-0360226-B1 | Drug for testing function of secreting adrenocorticotropic hormone | OTSUKA PHARMA CO LTD (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5217714-A | Administering interleukins, then measuring blood concentration of adrenocortocotropic hormones, glucocorticoids or other hormones | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0360226-A2 | Drug for testing function of secreting adrenocorticotropic hormone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-03-28 | — | — | EP | disclosed |