SCHEMBL28586232

SCHEMBL28586232

[c]1ccc(-c2ccc3oc4ccc(-c5cccnc5)cc4c3c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.47
CYP19A1 P11511 3/20 0.47
PIM1 P11309 2/20 0.46
PIM2 Q9P1W9 1/20 0.46
CYP1A2 P05177 2/20 0.44
CYP3A4 P08684 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP11B2 P19099 7/20 0.44
CYP11B1 P15538 6/20 0.44
CYP17A1 P05093 2/20 0.44
CLK4 Q9HAZ1 2/20 0.43
LMNA P02545 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C9 P11712 1/20 0.43
MAPK1 P28482 1/20 0.43
HIF1A Q16665 1/20 0.43
CHEK1 O14757 1/20 0.43
AURKA O14965 1/20 0.43
DAPK3 O43293 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29293277 0.91 CYP19A1 (0.54) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL14733823 0.89 CYP1A2 (0.56) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL21295953 0.89 PGR (0.45) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL21295715 0.87 PGR (0.44) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL28596821 0.86 PGR (0.45) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL23331717 0.85 CYP11B1 (0.50) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL13471315 0.85 PGR (0.56) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL12129586 0.84 PGR (0.58) PGRCYP19A1PIM1PIM2CYP1A2
SCHEMBL28590548 0.83 ATM (0.37) PIM1CYP2A6MAP4K4CDK9DYRK1A
SCHEMBL28590587 0.83 DYRK1A (0.45) CYP19A1LMNAJAK2MAP4K4GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed