Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | CCKAR | P32238 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | PYGM | P11217 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767982 | 1.00 | EPHX2 (0.49) | EPHX2GAAIDO1RIPK1MAPK10 | |
| SCHEMBL8273806 | 1.00 | EPHX2 (0.49) | EPHX2GAAIDO1RIPK1MAPK10 | |
| SCHEMBL10263516 | 0.84 | EPHX2 (0.50) | EPHX2GAAIDO1MAPK10NFKB1 | |
| SCHEMBL5311229 | 0.82 | RIPK1 (0.45) | RIPK1BRD4CRBNPYGLPYGM | |
| SCHEMBL14280762 | 0.81 | RIPK1 (0.42) | RIPK1BRD4CRBNPYGLPYGM | |
| SCHEMBL8273799 | 0.81 | EPHX2 (0.49) | EPHX2GAARIPK1NFKB1NFKB2 | |
| SCHEMBL29619167 | 0.81 | EPHX2 (0.49) | EPHX2GAARIPK1NFKB1NFKB2 | |
| SCHEMBL29900496 | 0.80 | EPHX2 (0.63) | EPHX2GAAIDO1MAPK10NFKB1 | |
| SCHEMBL651278 | 0.80 | EPHX2 (0.63) | EPHX2GAAIDO1MAPK10NFKB1 | |
| SCHEMBL4806148 | 0.80 | EPHX2 (0.63) | EPHX2GAAIDO1MAPK10NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107709301-B | Pyrazole derivative or pharmacologically acceptable salt thereof | 橘生药品工业株式会社 | 2021-06-22 | — | — | CN | disclosed |