Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4902321 | 1.00 | TLR4 (0.40) | TLR4FYNCYP2C9POLBHPGD | |
| SCHEMBL2852137 | 1.00 | TLR4 (0.40) | TLR4FYNCYP2C9POLBHPGD | |
| SCHEMBL4905710 | 1.00 | TLR4 (0.40) | TLR4FYNCYP2C9POLBHPGD | |
| SCHEMBL5836344 | 0.85 | TLR4 (0.42) | TLR4FYNCYP2C9MEN1KMT2A | |
| SCHEMBL14281259 | 0.85 | PKM (0.47) | CYP2C9POLBHPGDMEN1KMT2A | |
| SCHEMBL5836340 | 0.85 | TLR4 (0.42) | TLR4FYNCYP2C9MEN1KMT2A | |
| SCHEMBL6697654 | 0.85 | TLR4 (0.42) | TLR4FYNCYP2C9MEN1KMT2A | |
| SCHEMBL11019067 | 0.83 | TLR4 (0.41) | TLR4FYNCYP2C9MEN1KMT2A | |
| SCHEMBL8217513 | 0.83 | TLR4 (0.41) | TLR4FYNCYP2C9MEN1KMT2A | |
| SCHEMBL11019071 | 0.83 | TLR4 (0.41) | TLR4FYNCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10221114-B2 | Liquid crystal compound having tetrafluoro cyclohexadiene structure showing negative anisotropy, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2019-03-05 | — | — | US | disclosed |
| US-20160200980-A1 | LIQUID CRYSTAL COMPOUND HAVING TETRAFLUORO CYCLOHEXADIENE STRUCTURE SHOWING NEGATIVE ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| US-20160200980-A1 | LIQUID CRYSTAL COMPOUND HAVING TETRAFLUORO CYCLOHEXADIENE STRUCTURE SHOWING NEGATIVE ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2016-07-14 | — | — | US | disclosed |
| EP-2258695-B1 | CHROMAN DERIVATIVES AND USE THEREOF IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2258695-B1 | CHROMAN DERIVATIVES AND USE THEREOF IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2013-05-29 | — | — | EP | disclosed |
| EP-2258695-A2 | Chroman derivatives and use thereof in liquid crystal media | Merck Patent GmbH (DE) | 2010-12-08 | — | — | EP | disclosed |
| EP-2258695-A2 | Chroman derivatives and use thereof in liquid crystal media | Merck Patent GmbH (DE) | 2010-12-08 | — | — | EP | disclosed |
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-24 | — | — | US | disclosed |
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-01-24 | — | — | US | disclosed |
| EP-1831190-A2 | CHROMAN DERIVATIVES AND USE THEREOF IN LIQUID CRYSTAL MEDIA | Merck Patent GmbH (DE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006040009-A2 | CHROMAN DERIVATIVES AND USE THEREOF IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2006-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200980-A1 | LIQUID CRYSTAL COMPOUND HAVING TETRAFLUORO CYCLOHEXADIENE STRUCTURE SHOWING NEGATIVE ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | OCIAD2, CNOT1, OCIAD1 | TLR4 4014/4885FYN 531/4885CYP2C9 3316/4885 |
| US-10221114-B2 | Liquid crystal compound having tetrafluoro cyclohexadiene structure showing negative anisotropy, liquid crystal composition, and liquid crystal display device | OCIAD2, CNOT1, OCIAD1 | TLR4 4014/4885FYN 531/4885CYP2C9 3316/4885 |
| US-20080020148-A1 | Chromane Derivatives Method for Production and the Use Thereof | C1S, CHRM1, C1R | TLR4 2758/4885FYN 1194/4885CYP2C9 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.