SCHEMBL28587125

SCHEMBL28587125

CCCCCS(=O)(=O)N(CC)CC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.48
CNR2 P34972 1/20 0.44
CA2 P00918 6/20 0.43
CA1 P00915 1/20 0.36
NPC1 O15118 1/20 0.36
S1PR2 O95136 1/20 0.36
S1PR4 O95977 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
XBP1 P17861 1/20 0.36
S1PR1 P21453 1/20 0.36
MAPK1 P28482 1/20 0.36
AGTR1 P30556 1/20 0.36
HTT P42858 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9501865 0.97 FAAH (0.52) FAAHCNR2CA2CES1CES2
SCHEMBL10459109 0.97 FAAH (0.52) FAAHCNR2CA2CES1CES2
SCHEMBL27373743 0.92 CNR2 (0.45) FAAHCNR2CA2CA1NPC1
SCHEMBL14229169 0.91 CNR2 (0.46) FAAHCNR2CA2CA1CES1
SCHEMBL14229678 0.89 CNR2 (0.49) FAAHCNR2CA2CES1CES2
SCHEMBL6546381 0.89 FAAH (0.40) FAAHCNR2CA2CES1CES2
SCHEMBL14229874 0.85 CNR2 (0.45) FAAHCNR2CA2CA1CES1
SCHEMBL27905197 0.85 CA1 (0.50) FAAHCNR2CA2CA1CES1
SCHEMBL7856362 0.83 CNR2 (0.51) FAAHCNR2CA2CES1CES2
SCHEMBL14228922 0.83 CNR2 (0.47) FAAHCNR2CA2CA1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112903886-B Separation and detection method of 1-butylsulfonyl chloride related substances 四川科伦药物研究院有限公司 2024-05-24 CN disclosed
CN-112903886-A Separation and detection method of 1-butylsulfonyl chloride related substances 四川科伦药物研究院有限公司 2021-06-04 CN disclosed