SCHEMBL28587209

SCHEMBL28587209

CC(=Cc1cccc(C)c1C)[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.51
TSHR P16473 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
ALDH1A1 P00352 7/20 0.42
MITF O75030 2/20 0.42
LMNA P02545 2/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
JAK2 O60674 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C9 P11712 1/20 0.42
NTSR1 P30989 1/20 0.42
CYP2C19 P33261 1/20 0.42
KMT2A Q03164 1/20 0.42
ABL1 P00519 1/20 0.42
EGFR P00533 1/20 0.42
ABL2 P42684 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18543740 0.86 FBP1 (0.59) FBP1TSHRSMN1; SMN2ALDH1A1MITF
SCHEMBL9983817 0.79 FBP1 (0.47) FBP1SMN1; SMN2ALDH1A1MITFLMNA
SCHEMBL9983824 0.79 FBP1 (0.47) FBP1SMN1; SMN2ALDH1A1MITFLMNA
SCHEMBL9983828 0.79 FBP1 (0.47) FBP1SMN1; SMN2ALDH1A1MITFLMNA
SCHEMBL19439379 0.75 FBP1 (0.59) FBP1ALDH1A1MITFLMNAMAPT
SCHEMBL19439378 0.75 FBP1 (0.59) FBP1ALDH1A1MITFLMNAMAPT
SCHEMBL10718673 0.75 FBP1 (0.54) FBP1TSHRSMN1; SMN2ALDH1A1MITF
SCHEMBL22288209 0.75 FBP1 (0.46) FBP1TSHRSMN1; SMN2ALDH1A1MITF
SCHEMBL8675526 0.75 FBP1 (0.54) FBP1TSHRSMN1; SMN2ALDH1A1MITF
SCHEMBL8675524 0.75 FBP1 (0.54) FBP1TSHRSMN1; SMN2ALDH1A1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961093-A Method for reducing C = C double bond of nitroolefin with high selectivity 北京化工大学 2021-06-15 CN disclosed