Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | DDX3X | O00571 | 2/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22532423 | 0.87 | HDAC6 (0.56) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5557794 | 0.82 | HDAC6 (0.52) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28573282 | 0.82 | HDAC6 (0.64) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL28568674 | 0.80 | RXFP1 (0.62) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6154791 | 0.79 | HDAC6 (0.54) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12015939 | 0.79 | NPC1 (0.73) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13442817 | 0.77 | MAPT (0.60) | NPC1RAB9AMEN1KMT2ACSNK2A2 | |
| SCHEMBL13244789 | 0.77 | KDM4E (0.56) | NPC1RAB9AMEN1KMT2ARXFP1 | |
| SCHEMBL7324615 | 0.77 | CA1 (0.65) | HDAC6NPC1RAB9AMEN1KMT2A | |
| SCHEMBL12425519 | 0.76 | CSNK2A2 (0.51) | NPC1RAB9AMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | claimed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | claimed |
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | disclosed |