Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.64 |
| ▸ | RARA | P10276 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | RARG | P13631 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154791 | 0.91 | HDAC6 (0.54) | HDAC6RARARARBRARGNPC1 | |
| SCHEMBL28587303 | 0.82 | HDAC6 (0.62) | HDAC6NPC1MEN1KMT2ADHODH | |
| SCHEMBL15515850 | 0.79 | KDM4E (0.60) | RARARARBRARGNPC1MEN1 | |
| SCHEMBL491414 | 0.79 | MEN1 (0.64) | RARARARBRARGNPC1MEN1 | |
| SCHEMBL9176722 | 0.78 | SMN1; SMN2 (0.72) | NPC1MEN1KMT2AGBA1MAPT | |
| SCHEMBL28574866 | 0.77 | HDAC6 (0.61) | HDAC6NPC1MEN1KMT2AMAPT | |
| SCHEMBL24233043 | 0.77 | KMT2A (0.71) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL2423069 | 0.77 | KDM4E (0.74) | NPC1LMNARAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2179717 | 0.76 | TRPM8 (0.58) | RARARARBRARGNPC1MEN1 | |
| SCHEMBL5557794 | 0.76 | HDAC6 (0.52) | HDAC6NPC1MEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | claimed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | claimed |
| CN-112981436-B | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2022-02-01 | — | — | CN | disclosed |
| CN-112981436-A | Method for synthesizing 2-amino-1, 3, 4-thiadiazole derivative through electrochemical oxidation | 昆明学院 | 2021-06-18 | — | — | CN | disclosed |