SCHEMBL28587516

SCHEMBL28587516

NC(=O)OC1CCN(NC(=O)COc2ccc(Cl)c(F)c2)CC1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ATF4 P18848 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21882030 0.87 ATF4 (0.78) ATF4
SCHEMBL28724353 0.86 ATF4 (0.70) ATF4
SCHEMBL23920226 0.85 ATF4 (0.75) ATF4
SCHEMBL28577681 0.85 ATF4 (0.69) ATF4
SCHEMBL28588174 0.84 ATF4 (0.57) ATF4
SCHEMBL28590128 0.84 ATF4 (0.52) ATF4
SCHEMBL21819613 0.84 ATF4 (1.00) ATF4
SCHEMBL28906768 0.84 ATF4 (0.60) ATF4
SCHEMBL24997267 0.84 ATF4 (0.77) ATF4
SCHEMBL21819714 0.82 ATF4 (0.88) ATF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912082-A Integrated stress pathway inhibitors 普拉西斯生物技术有限责任公司 2021-06-04 CN disclosed