Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.50 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.50 |
| ▸ | PI4KA | P42356 | 1/20 | 0.50 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.50 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30386502 | 1.00 | PIM1 (0.53) | PIM1PIM2CYP1A2KDM4ENPC1 | |
| SCHEMBL13967409 | 0.86 | PIK3CA (0.54) | PIM1PIM2CYP1A2KDM4ENPC1 | |
| SCHEMBL12927747 | 0.84 | PIK3CA (0.62) | PIM1PIM2CYP1A2KDM4ENPC1 | |
| SCHEMBL12067379 | 0.84 | PIK3CA (0.47) | PIM1PIM2CYP1A2KDM4ENPC1 | |
| SCHEMBL12850681 | 0.83 | LMNA (0.66) | CYP1A2NPC1RAB9APIK3CAPIK3CD | |
| SCHEMBL31119195 | 0.82 | GAA (0.65) | CYP1A2KDM4ENPC1RAB9APGR | |
| SCHEMBL14097677 | 0.82 | GAA (0.65) | CYP1A2KDM4ENPC1RAB9APGR | |
| SCHEMBL12928185 | 0.82 | PIK3CA (0.41) | PIM1PIM2CYP1A2KDM4ENPC1 | |
| SCHEMBL12928413 | 0.81 | NT5E (0.56) | CYP1A2KDM4ENPC1CYP2C19HTT | |
| SCHEMBL14681667 | 0.81 | PIK3CA (0.53) | PIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112209894-B | 5-aryl substituted 2-aminobenzoxazole derivative, preparation method and application thereof | 贵州医科大学 | 2023-06-06 | — | — | CN | disclosed |
| CN-112209894-A | 5-aryl substituted 2-aminobenzoxazole derivative, preparation method and application thereof | 贵州医科大学 | 2021-01-12 | — | — | CN | disclosed |