Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21306867 | 0.84 | CA12 (0.60) | SMN1; SMN2KMT2AMEN1RAB9ALMNA | |
| SCHEMBL28576874 | 0.83 | PRSS1 (0.52) | SMN1; SMN2KMT2AMEN1MAPTTSHR | |
| SCHEMBL27639799 | 0.78 | GAA (0.59) | SMN1; SMN2KMT2AMEN1MAPTGAA | |
| SCHEMBL19860802 | 0.78 | APLNR (0.51) | KMT2AMEN1POLBCA12CA1 | |
| SCHEMBL1660322 | 0.77 | RECQL (0.77) | RECQLSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL4221613 | 0.77 | RECQL (0.77) | RECQLSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL30506314 | 0.77 | RECQL (0.77) | RECQLSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL29144074 | 0.77 | KDM4C (0.45) | RECQLSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL16935790 | 0.74 | RECQL (0.58) | RECQLSMN1; SMN2KMT2AMEN1MAPT | |
| SCHEMBL18373541 | 0.74 | RECQL (0.58) | RECQLSMN1; SMN2KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964684-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117964683-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |