Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST14 | Q9Y5Y6 | 5/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.47 |
| ▸ | CCR9 | P51686 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 4/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28588265 | 1.00 | ST14 (0.47) | ST14PRSS1PRSS2PRSS3CCR9 | |
| SCHEMBL28583287 | 0.92 | CCR9 (0.46) | ST14PRSS1PRSS2PRSS3CCR9 | |
| SCHEMBL28583288 | 0.92 | CCR9 (0.46) | ST14PRSS1PRSS2PRSS3CCR9 | |
| SCHEMBL30180776 | 0.88 | CCR9 (0.50) | CCR9SCN9AF10CCR3 | |
| SCHEMBL28583333 | 0.88 | CCR9 (0.50) | CCR9SCN9AF10CCR3 | |
| SCHEMBL28583332 | 0.88 | CCR9 (0.50) | CCR9SCN9AF10CCR3 | |
| SCHEMBL25017363 | 0.85 | ST14 (0.55) | ST14PRSS1PRSS2PRSS3F10 | |
| SCHEMBL28582742 | 0.84 | CCR9 (0.53) | CCR9F10SMYD3PRKAA2 | |
| SCHEMBL28582741 | 0.84 | CCR9 (0.53) | CCR9F10SMYD3PRKAA2 | |
| SCHEMBL30180499 | 0.83 | CCR9 (0.46) | CCR9SCN9AF10PRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |