Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 2/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28583287 | 1.00 | CCR9 (0.46) | CCR9SCN9AF10CCR3NPC1 | |
| SCHEMBL28588267 | 0.92 | ST14 (0.47) | CCR9SCN9AF10CCR3NPC1 | |
| SCHEMBL28588265 | 0.92 | ST14 (0.47) | CCR9SCN9AF10CCR3NPC1 | |
| SCHEMBL28575219 | 0.87 | F2 (0.48) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL25016086 | 0.87 | F2 (0.48) | F10F2ST14PRSS1PRSS2 | |
| SCHEMBL28583333 | 0.86 | CCR9 (0.50) | CCR9SCN9AF10CCR3CNR1 | |
| SCHEMBL30180776 | 0.86 | CCR9 (0.50) | CCR9SCN9AF10CCR3CNR1 | |
| SCHEMBL28583332 | 0.86 | CCR9 (0.50) | CCR9SCN9AF10CCR3CNR1 | |
| SCHEMBL28578395 | 0.84 | F10 (0.48) | F10CCR3NPC1F2ST14 | |
| SCHEMBL28578396 | 0.84 | F10 (0.48) | F10CCR3NPC1F2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |