Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25017976 | 1.00 | F10 (0.45) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL30180687 | 1.00 | F10 (0.45) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25017497 | 1.00 | F10 (0.45) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL30180564 | 0.91 | F10 (0.43) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25016443 | 0.91 | F10 (0.43) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL28578329 | 0.91 | F10 (0.43) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL21822364 | 0.91 | F10 (0.55) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL25015955 | 0.90 | F10 (0.48) | F10NOD2NOD1KMT2AMEN1 | |
| SCHEMBL21822191 | 0.90 | CCR2 (0.37) | — | |
| SCHEMBL21822188 | 0.90 | CCR2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |