Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.58 |
| ▸ | LCK | P06239 | 1/20 | 0.58 |
| ▸ | FYN | P06241 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28573801 | 0.96 | FFAR3 (0.64) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9681158 | 0.91 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL28953560 | 0.91 | — | — | |
| Acetic Acid SCHEMBL28281801 | 0.91 | — | — | |
| Acetic Acid SCHEMBL9244985 | 0.91 | FFAR3 (0.70) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9682311 | 0.87 | — | — | |
| Acetic Acid SCHEMBL9681819 | 0.87 | FFAR3 (0.64) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9680543 | 0.87 | FFAR3 (0.64) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL563050 | 0.87 | — | — | |
| Acetic Acid SCHEMBL8892546 | 0.87 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876359-B | Preparation method of dimethyl 2, 6-naphthalene dicarboxylate | 上海中化科技有限公司 | 2022-11-01 | — | — | CN | claimed |
| CN-112876359-A | Preparation method of dimethyl 2, 6-naphthalenedicarboxylate | 上海中化科技有限公司 | 2021-06-01 | — | — | CN | claimed |
| CN-112876359-B | Preparation method of dimethyl 2, 6-naphthalene dicarboxylate | 上海中化科技有限公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-112876359-A | Preparation method of dimethyl 2, 6-naphthalenedicarboxylate | 上海中化科技有限公司 | 2021-06-01 | — | — | CN | disclosed |