Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.70 |
| ▸ | LCK | P06239 | 1/20 | 0.70 |
| ▸ | FYN | P06241 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28953560 | 1.00 | — | — | |
| Acetic Acid SCHEMBL9681819 | 0.95 | FFAR3 (0.64) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL28573801 | 0.95 | FFAR3 (0.64) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL9682311 | 0.95 | — | — | |
| Acetic Acid SCHEMBL9680543 | 0.95 | FFAR3 (0.64) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL7940742 | 0.95 | — | — | |
| Acetic Acid SCHEMBL15529133 | 0.95 | FFAR3 (0.78) | FFAR3LCKFYNLMNATSHR | |
| Acetic Acid SCHEMBL4905548 | 0.95 | — | — | |
| Acetic Acid SCHEMBL1179481 | 0.95 | — | — | |
| Acetic Acid SCHEMBL28588362 | 0.91 | FFAR3 (0.58) | FFAR3LCKFYNLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108997284-B | Method for synthesizing chlorophthalic anhydride in continuous flow micro-channel reactor | 山东冠森高分子材料科技股份有限公司 | 2022-05-03 | — | — | CN | claimed |
| CN-108610314-B | Method for synthesizing biphenyl dianhydride in continuous flow microchannel reactor | 山东冠森高分子材料科技股份有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-5091564-A | Catalytic oxidation of tetramethyldiphenyl sulfone | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | claimed |
| CN-108997285-B | Method for synthesizing benzophenone tetracarboxylic dianhydride in continuous flow microchannel reactor | 山东冠森高分子材料科技股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-108997284-B | Method for synthesizing chlorophthalic anhydride in continuous flow micro-channel reactor | 山东冠森高分子材料科技股份有限公司 | 2022-05-03 | — | — | CN | disclosed |
| CN-108610314-B | Method for synthesizing biphenyl dianhydride in continuous flow microchannel reactor | 山东冠森高分子材料科技股份有限公司 | 2022-03-15 | — | — | CN | disclosed |
| CN-108003006-A | A kind of method that terephthalic acid (TPA) and M-phthalic acid are produced using C8 aronmatic as raw material | 杭州多向流化学科技有限公司 | 2018-05-08 | — | — | CN | disclosed |
| US-5091564-A | Catalytic oxidation of tetramethyldiphenyl sulfone | NEW JAPAN CHEMICAL CO., LTD. (JP) | 1992-02-25 | — | — | US | disclosed |