Ethylene

Ethylene

SCHEMBL28588441

C=C.CCCCCCCCCCCCc1nccn1O

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 4/20 0.40
TLR8 Q9NR97 2/20 0.38
ALDH1A1 P00352 2/20 0.36
POLB P06746 1/20 0.36
KMT2A Q03164 1/20 0.36
PTGS2 P35354 3/20 0.34
ESR1 P03372 2/20 0.34
ADRA2A P08913 2/20 0.34
ADORA3 P0DMS8 2/20 0.34
TACR2 P21452 2/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
KCNH2 Q12809 2/20 0.34
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
SHBG P04278 1/20 0.34
TP53 P04637 1/20 0.34
CYP3A4 P08684 1/20 0.34
HSPD1 P10809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28300533 0.96 TLR7 (0.42) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL25273826 0.96 TLR7 (0.42) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL21494426 0.87 FAAH (0.41)
SCHEMBL4890347 0.81
SCHEMBL4067299 0.80 TLR8 (0.44) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL1898631 0.80 TLR8 (0.44) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL2229133 0.80 TLR8 (0.44) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL1526997 0.80 TLR8 (0.44) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL301893 0.80 TLR8 (0.44) TLR7TLR8ALDH1A1POLBKMT2A
SCHEMBL2231125 0.80 TLR8 (0.44) TLR7TLR8ALDH1A1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112920640-A Shear thickening fluid, paint, preparation method thereof and application of paint 湘潭大学 2021-06-08 CN disclosed