Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23550746 | 0.88 | GPR3 (0.69) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL85621 | 0.82 | GPR3 (1.00) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL3907848 | 0.80 | GPR3 (0.95) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL3259024 | 0.80 | GPR3 (0.70) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL22490105 | 0.80 | GPR3 (0.70) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL3854784 | 0.77 | GPR3 (0.66) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL21244207 | 0.77 | GPR3 (0.66) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL30659940 | 0.77 | GPR3 (0.66) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL18771828 | 0.77 | GPR3 (0.66) | GPR3CYP1A2ALDH1A1HSD17B10HPGD | |
| SCHEMBL17532763 | 0.77 | GPR3 (0.60) | GPR3CYP1A2ALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045496-B | Method for selectively synthesizing dihydrophenanthridine or phenanthridine compounds | 河南师范大学 | 2022-04-26 | — | — | CN | disclosed |
| CN-113045496-A | Method for selectively synthesizing dihydrophenanthridine or phenanthridine compounds | 河南师范大学 | 2021-06-29 | — | — | CN | disclosed |