Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL4451952 | 0.85 | — | — | |
| SCHEMBL27173955 | 0.85 | TSHR (1.00) | TSHRALDH1A1TDP1 | |
| SCHEMBL67637 | 0.85 | — | — | |
| Hydrogen Sulfide SCHEMBL27511962 | 0.82 | — | — | |
| Methoxymethane SCHEMBL28021870 | 0.82 | TSHR (0.93) | TSHRALDH1A1TDP1 | |
| SCHEMBL27850925 | 0.82 | — | — | |
| Water SCHEMBL20578221 | 0.82 | TSHR (0.93) | TSHRALDH1A1TDP1 | |
| Amylene Hydrate SCHEMBL9870861 | 0.80 | ALDH1A1 (0.77) | TSHRALDH1A1TDP1 | |
| Bicarbonate SCHEMBL16738136 | 0.78 | TSHR (0.42) | TSHRALDH1A1TDP1FFAR3HMGCR | |
| Bicarbonate SCHEMBL28698543 | 0.78 | TSHR (0.42) | TSHRALDH1A1TDP1FFAR3HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107922535-B | Powder mixture | DIC株式会社 | 2021-06-29 | — | — | CN | disclosed |