Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 6/20 | 0.60 |
| ▸ | MGAM | O43451 | 10/20 | 0.50 |
| ▸ | AMY1A | P0DUB6 | 10/20 | 0.50 |
| ▸ | GAA | P10253 | 10/20 | 0.50 |
| ▸ | SI | P14410 | 10/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 10/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502829 | 0.90 | GAA (0.56) | F12MGAMAMY1AGAASI | |
| SCHEMBL28580426 | 0.88 | MGAM (0.60) | F12MGAMAMY1AGAASI | |
| SCHEMBL28588844 | 0.84 | MGAM (0.51) | F12MGAMAMY1AGAASI | |
| SCHEMBL31749664 | 0.82 | MGAM (0.45) | F12MGAMAMY1AGAASI | |
| SCHEMBL31749537 | 0.81 | F12 (0.46) | F12MGAMAMY1AGAASI | |
| SCHEMBL29502828 | 0.78 | KCNMA1 (0.50) | F12MGAMAMY1AGAASI | |
| SCHEMBL31749637 | 0.76 | MGAM (0.50) | F12MGAMAMY1AGAASI | |
| SCHEMBL31749736 | 0.76 | ELANE (0.48) | F12MGAMAMY1AGAASI | |
| SCHEMBL31749631 | 0.76 | MGAM (0.45) | F12MGAMAMY1AGAASI | |
| SCHEMBL28594361 | 0.76 | GAA (0.63) | F12MGAMAMY1AGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045508-B | Method for synthesizing diaminoalkene by NBS (N-bromosuccinimide) to promote polarity reversal of enaminone | 河南科技大学 | 2022-04-22 | — | — | CN | disclosed |
| CN-113045508-A | Method for synthesizing diaminoalkene by NBS (N-bromosuccinimide) to promote polarity reversal of enaminone | 河南科技大学 | 2021-06-29 | — | — | CN | disclosed |