Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166823 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL28577996 | 1.00 | CHRNB2 (0.51) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL3071569 | 0.90 | SLC6A2 (0.50) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL23791472 | 0.90 | SLC6A2 (0.50) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL23632246 | 0.90 | SLC6A2 (0.50) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL23475081 | 0.84 | CHRNB2 (0.51) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL13761577 | 0.84 | CHRNB2 (0.51) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL3004210 | 0.83 | SLC6A4 (0.49) | CHRNB2CHRNA4HTR2ASLC6A2SLC6A4 | |
| SCHEMBL19582779 | 0.82 | CHRNB2 (0.55) | CHRNB2CHRNA4ROCK1ROCK2PRKX | |
| SCHEMBL15650257 | 0.82 | CHRNB2 (0.55) | CHRNB2CHRNA4ROCK1ROCK2PRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |