Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 15/20 | 0.56 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.56 |
| ▸ | PRCP | P42785 | 3/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590668 | 1.00 | USP30 (0.58) | USP30HCRTR1HCRTR2PRCP | |
| SCHEMBL2707200 | 0.96 | USP30 (0.52) | USP30HCRTR1HCRTR2 | |
| SCHEMBL13070464 | 0.96 | USP30 (0.52) | USP30HCRTR1HCRTR2 | |
| SCHEMBL18462768 | 0.96 | USP30 (0.52) | USP30HCRTR1HCRTR2 | |
| SCHEMBL2706118 | 0.96 | USP30 (0.52) | USP30HCRTR1HCRTR2 | |
| SCHEMBL14985689 | 0.95 | HCRTR1 (0.51) | USP30HCRTR1HCRTR2 | |
| SCHEMBL204876 | 0.95 | HCRTR1 (0.51) | USP30HCRTR1HCRTR2 | |
| SCHEMBL2707183 | 0.95 | HCRTR1 (0.51) | USP30HCRTR1HCRTR2 | |
| SCHEMBL16790639 | 0.93 | HCRTR1 (0.52) | USP30HCRTR1HCRTR2PRCP | |
| SCHEMBL19400821 | 0.92 | PRCP (0.52) | USP30HCRTR1HCRTR2PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884068-B | 1-cyano-pyrrolidine derivatives as DUB inhibitors | 特殊治疗有限公司 | 2021-02-26 | — | — | CN | disclosed |