Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.52 |
| ▸ | HCRTR2 | O43614 | 16/20 | 0.52 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590668 | 0.93 | USP30 (0.58) | HCRTR1HCRTR2USP30PRCP | |
| SCHEMBL28590669 | 0.93 | USP30 (0.58) | HCRTR1HCRTR2USP30PRCP | |
| SCHEMBL2707183 | 0.90 | HCRTR1 (0.51) | HCRTR1HCRTR2USP30 | |
| SCHEMBL14985689 | 0.90 | HCRTR1 (0.51) | HCRTR1HCRTR2USP30 | |
| SCHEMBL204876 | 0.90 | HCRTR1 (0.51) | HCRTR1HCRTR2USP30 | |
| SCHEMBL2706118 | 0.89 | USP30 (0.52) | HCRTR1HCRTR2USP30 | |
| SCHEMBL13070464 | 0.89 | USP30 (0.52) | HCRTR1HCRTR2USP30 | |
| SCHEMBL18462768 | 0.89 | USP30 (0.52) | HCRTR1HCRTR2USP30 | |
| SCHEMBL2707200 | 0.89 | USP30 (0.52) | HCRTR1HCRTR2USP30 | |
| SCHEMBL9881861 | 0.87 | HCRTR1 (0.54) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150232455-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2015-08-20 | — | — | US | disclosed |
| US-20150158909-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2015-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232455-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | HCRTR1 3834/4885HCRTR2 4467/4885USP30 1431/4885 |
| US-20150158909-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, EIF2AK2, MAVS | HCRTR1 3834/4885HCRTR2 4467/4885USP30 1431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.