Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 14/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 11/20 | 0.45 |
| ▸ | TUBB | P07437 | 11/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 11/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 11/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 11/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 11/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 11/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 11/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 11/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 11/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 11/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 11/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 11/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 11/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28590803 | 1.00 | TUBB1 (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28590597 | 0.84 | POLB (0.43) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28045131 | 0.79 | TUBB1 (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28593409 | 0.76 | MAPT (0.55) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28593411 | 0.76 | MAPT (0.55) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27852286 | 0.75 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28590080 | 0.74 | GAA (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28590596 | 0.74 | MRGPRX1 (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28590087 | 0.74 | GAA (0.44) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28592567 | 0.72 | MAPT (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112375042-A | Trimethoxy styryl six-membered ring and pyrazolopyrimidine compound, preparation and application thereof | 安徽医科大学 | 2021-02-19 | — | — | CN | disclosed |