Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 14/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 11/20 | 0.57 |
| ▸ | TUBB | P07437 | 11/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 11/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 11/20 | 0.57 |
| ▸ | TUBA4A | P68366 | 11/20 | 0.57 |
| ▸ | TUBB4B | P68371 | 11/20 | 0.57 |
| ▸ | TUBB3 | Q13509 | 11/20 | 0.57 |
| ▸ | TUBB2A | Q13885 | 11/20 | 0.57 |
| ▸ | TUBB8 | Q3ZCM7 | 11/20 | 0.57 |
| ▸ | TUBA3E | Q6PEY2 | 11/20 | 0.57 |
| ▸ | TUBA1A | Q71U36 | 11/20 | 0.57 |
| ▸ | TUBA1C | Q9BQE3 | 11/20 | 0.57 |
| ▸ | TUBB6 | Q9BUF5 | 11/20 | 0.57 |
| ▸ | TUBB2B | Q9BVA1 | 11/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | DHFR | P00374 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28045187 | 0.85 | GLA (0.57) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27852286 | 0.81 | TUBB1 (0.61) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL23743201 | 0.79 | TUBB1 (0.60) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28590807 | 0.79 | TUBB1 (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL28590803 | 0.79 | TUBB1 (0.45) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9189623 | 0.77 | TUBB4A (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL21005800 | 0.77 | TUBB4A (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9189630 | 0.77 | TUBB4A (0.65) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Bromide SCHEMBL28082033 | 0.76 | TUBB4A (0.63) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4608533 | 0.75 | CYP1A1 (0.79) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198820-A | Substituted pyrimidine compound containing isothiourea perssad and preparation method and application thereof | OCEAN UNIV CHINA | 2015-12-30 | — | — | CN | disclosed |