Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 6/20 | 0.51 |
| ▸ | CA2 | P00918 | 6/20 | 0.51 |
| ▸ | CA4 | P22748 | 6/20 | 0.51 |
| ▸ | CA9 | Q16790 | 6/20 | 0.51 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.51 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333929 | 0.90 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL10989449 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL23001698 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL28604810 | 0.88 | SMN1; SMN2 (0.75) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL1753520 | 0.88 | TP53 (0.75) | SMN1; SMN2TP53ALOX12MAPTSLC5A1 | |
| SCHEMBL28691622 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL28595758 | 0.85 | SMN1; SMN2 (0.70) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL30423580 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL28595074 | 0.82 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53ALOX12MAPTCA1 | |
| SCHEMBL10983505 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53ALOX12MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061138-B | Triazole [5,4-d ] pyrimidinone tricyclic compound, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-113061138-A | Triazole [5,4-d ] pyrimidone tricyclic compound and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2021-07-02 | — | — | CN | disclosed |