Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA4 | P22748 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 4/20 | 0.47 |
| ▸ | SLC5A2 | P31639 | 4/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11333929 | 0.86 | SMN1; SMN2 (0.79) | SMN1; SMN2TP53ALOX12KDM4EALDH1A1 | |
| SCHEMBL28591502 | 0.85 | SMN1; SMN2 (0.77) | SMN1; SMN2TP53ALOX12KDM4EALDH1A1 | |
| SCHEMBL10989449 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2TP53ALOX12KDM4EMAPT | |
| SCHEMBL23001698 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2TP53ALOX12KDM4EALDH1A1 | |
| SCHEMBL28604810 | 0.84 | SMN1; SMN2 (0.75) | SMN1; SMN2TP53ALOX12ALDH1A1MAPT | |
| SCHEMBL1753520 | 0.83 | TP53 (0.75) | SMN1; SMN2TP53ALOX12KDM4EALDH1A1 | |
| SCHEMBL28691622 | 0.82 | SMN1; SMN2 (1.00) | SMN1; SMN2TP53ALOX12KDM4EALDH1A1 | |
| SCHEMBL29629572 | 0.79 | KDM4E (0.61) | SMN1; SMN2ALOX12KDM4EALDH1A1MAPT | |
| SCHEMBL28595074 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53ALOX12ALDH1A1MAPT | |
| SCHEMBL30423580 | 0.78 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53ALOX12ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061138-B | Triazole [5,4-d ] pyrimidinone tricyclic compound, and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-113061138-A | Triazole [5,4-d ] pyrimidone tricyclic compound and preparation method and application thereof | 中国科学院新疆理化技术研究所 | 2021-07-02 | — | — | CN | disclosed |