SCHEMBL28592192

SCHEMBL28592192

Oc1ccccc1-c1ccc(-c2cccnc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 5/20 0.58
MKNK2 Q9HBH9 5/20 0.58
ALDH1A1 P00352 2/20 0.57
HPGD P15428 1/20 0.57
BCL2L1 Q07817 1/20 0.57
HSD17B10 Q99714 1/20 0.57
CYP2A6 P11509 4/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
PTGS2 P35354 1/20 0.53
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
IKBKB O14920 1/20 0.49
ERN1 O75460 1/20 0.49
CYP11B2 P19099 3/20 0.49
CYP11B1 P15538 3/20 0.49
CYP19A1 P11511 2/20 0.49
KIF11 P52732 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28606690 0.98 MKNK1 (0.56) MKNK1MKNK2ALDH1A1HPGDBCL2L1
SCHEMBL28598273 0.98 MKNK1 (0.56) MKNK1MKNK2ALDH1A1HPGDBCL2L1
SCHEMBL28919156 0.98 MKNK1 (0.56) MKNK1MKNK2ALDH1A1HPGDBCL2L1
SCHEMBL1155160 0.92 ALDH1A1 (0.60) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
SCHEMBL30070521 0.92 ALDH1A1 (0.60) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
Hydrochloric Acid SCHEMBL21412299 0.90 ALDH1A1 (0.58) ALDH1A1HPGDBCL2L1HSD17B10CYP2A6
SCHEMBL29266807 0.86 CYP2A6 (0.68) MKNK1MKNK2ALDH1A1HPGDHSD17B10
SCHEMBL28607093 0.86 ALDH1A1 (0.52) MKNK1MKNK2ALDH1A1HPGDBCL2L1
SCHEMBL29228088 0.84 MKNK1 (0.50) MKNK1MKNK2ALDH1A1HPGDBCL2L1
SCHEMBL28286304 0.84 MKNK1 (0.53) MKNK1MKNK2ALDH1A1CYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961102-B Metal complex and electron transport material using the same 大电株式会社 2024-03-12 CN disclosed
CN-109689665-B Metal complex and electron transport material using the same 大电株式会社 2021-10-01 CN disclosed
CN-112961102-A Metal complex and electron transport material using the same 大电株式会社 2021-06-15 CN disclosed