SCHEMBL2859232

SCHEMBL2859232

CC(O)Cc1ccc(O)cc1C(=O)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
USP2 O75604 1/20 0.51
GAA P10253 1/20 0.51
KEAP1 Q14145 1/20 0.51
NFE2L2 Q16236 1/20 0.51
HPGD P15428 3/20 0.46
LMNA P02545 3/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 2/20 0.46
BCL2 P10415 2/20 0.46
MCL1 Q07820 2/20 0.46
PGR P06401 1/20 0.46
CYP2D6 P10635 1/20 0.46
SLC6A2 P23975 1/20 0.46
PDE4A P27815 1/20 0.46
MAPK1 P28482 1/20 0.46
CYP2C19 P33261 1/20 0.46
HRH1 P35367 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2862128 0.88 MEN1 (0.55) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL2855480 0.86 MEN1 (0.49) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL27657200 0.83 AKR1C3 (0.48) KMT2AGAAHPGDALDH1A1CYP1A2
SCHEMBL27536907 0.82 MEN1 (0.48) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL5795785 0.81 KMT2A (0.50) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL5795787 0.81 KMT2A (0.50) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL2868205 0.77 MEN1 (0.56) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL7753424 0.75 GAA (0.47) MEN1KMT2AUSP2GAAKEAP1
SCHEMBL27962980 0.75 AKR1C3 (0.43) GAAHPGDLMNAALDH1A1BCL2
SCHEMBL11514944 0.74 MEN1 (0.55) MEN1KMT2AUSP2GAAKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
CN-1757130-A Polymer electrolyte material, polymer electrolyte part, film electrode composite element and polymer electrolyte fuel cells TORAY INDUSTRIES (JP) 2006-04-05 CN disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed