Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | TYR | P14679 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302289 | 0.89 | MEN1 (0.53) | MEN1KMT2ACYP3A4MAPTTYR | |
| SCHEMBL8340319 | 0.85 | TYR (0.56) | MEN1KMT2ACYP3A4MAPTTYR | |
| Benzene SCHEMBL11504828 | 0.85 | MAPT (0.61) | MEN1KMT2ACYP3A4MAPTTYR | |
| SCHEMBL28891018 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL31405271 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28412366 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL11002989 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL9559479 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL1534314 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 | |
| SCHEMBL28348884 | 0.84 | LIPG (0.51) | BIDMCL1BCL2L1BAK1KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133834-A | REACTING HYDROXYLAMINE WITH A KETONE, IRON CATALYSTS | ALLIED CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | claimed |
| US-4133834-A | REACTING HYDROXYLAMINE WITH A KETONE, IRON CATALYSTS | ALLIED CHEMICAL CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |