SCHEMBL28593151

SCHEMBL28593151

c1ccc2nc(-c3ccc4ccc5cccnc5c4n3)ccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.59
CYP3A4 P08684 4/20 0.59
TP53 P04637 4/20 0.59
CYP2D6 P10635 3/20 0.59
LMNA P02545 3/20 0.59
MAPT P10636 3/20 0.59
CCR1 P32246 3/20 0.59
CCR5 P51681 3/20 0.59
CCR8 P51685 3/20 0.59
ALOX15 P16050 3/20 0.59
PMP22 Q01453 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
GMNN O75496 2/20 0.59
THPO P40225 2/20 0.59
TSHR P16473 2/20 0.59
HSP90AA1 P07900 1/20 0.59
MMP2 P08253 1/20 0.59
MMP9 P14780 1/20 0.59
NFKB1 P19838 1/20 0.59
MMP8 P22894 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29228108 0.98 KDM4E (0.57) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL17491090 0.90 CCR1 (0.52) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL14184271 0.89 CCR1 (0.64) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL17899316 0.88 CCR1 (0.76) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL22101154 0.88 CCR1 (0.76) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL29413987 0.88 CCR1 (0.76) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL22281680 0.88 NPC1 (0.51) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL21171705 0.88 LMNA (0.46) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL23016166 0.87 NPC1 (0.50) KDM4ECYP3A4TP53CYP2D6LMNA
SCHEMBL19763005 0.85 NPC1 (0.49) KDM4ECYP3A4TP53CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112961102-B Metal complex and electron transport material using the same 大电株式会社 2024-03-12 CN disclosed
CN-109689665-B Metal complex and electron transport material using the same 大电株式会社 2021-10-01 CN disclosed
CN-112961102-A Metal complex and electron transport material using the same 大电株式会社 2021-06-15 CN disclosed