SCHEMBL2859436

SCHEMBL2859436

CC(I)OC(=O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KLK7 P49862 8/20 0.57
POLB P06746 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
CHRM1 P11229 5/20 0.49
CHRM3 P20309 5/20 0.49
CHRM2 P08172 4/20 0.49
CHRM4 P08173 4/20 0.49
TDP1 Q9NUW8 1/20 0.48
ALDH1A1 P00352 2/20 0.48
HSD17B10 Q99714 2/20 0.48
LMNA P02545 2/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
KMT2A Q03164 2/20 0.46
CYP3A4 P08684 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.44
CHRM5 P08912 1/20 0.44
THRB P10828 1/20 0.44
CYP2C9 P11712 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27718810 0.84 KLK7 (0.60) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL2864946 0.81 KLK7 (0.57) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL360678 0.81 KLK7 (0.66) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL2859574 0.81 KLK7 (0.57) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL360679 0.81 KLK7 (0.66) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL12047330 0.79 KLK7 (0.64) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL360232 0.78 KLK7 (0.54) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL360231 0.78 KLK7 (0.54) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL5968318 0.78 L3MBTL1 (0.54) KLK7POLBL3MBTL1CHRM1CHRM3
SCHEMBL8047739 0.78 L3MBTL1 (0.54) KLK7POLBL3MBTL1CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1795581-B1 LUBRICATING OIL COMPOSITION CONTAINING ACRYLIC POLYMER KURARAY CO (JP) 2018-09-19 EP disclosed
US-7718588-B2 Lubricating oil additive containing acrylic polymer and lubricating oil compositions KURARAY CO., LTD. (JP) 2010-05-18 US disclosed
US-20080058234-A1 Lubricating Oil Additive Containing Acrylic Polymer and Lubricating Oil Compositions KURARAY CO., LTD. (JP) 2008-03-06 US disclosed
EP-1795581-A1 LUBRICATING OIL ADDITIVE CONTAINING ACRYLIC POLYMER AND LUBRICATING OIL COMPOSITIONS KURARAY CO., LTD. (JP) 2007-06-13 EP disclosed