Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28595015

N.O=S(=O)(OCc1ccc(Cl)cc1)C(F)(F)F

nearest known ligand 0.63

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.63
KMT2A Q03164 4/20 0.45
CA1 P00915 5/20 0.44
CA9 Q16790 3/20 0.42
IDO1 P14902 2/20 0.42
AGXT P21549 2/20 0.42
PTPRZ1 P23471 1/20 0.40
NR4A2 P43354 2/20 0.39
MEN1 O00255 2/20 0.39
APP P05067 1/20 0.36
MAOB P27338 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5676893 0.98 CA2 (0.65) CA2KMT2ACA1CA9IDO1
Ammonia Solution, Strong SCHEMBL28581052 0.84 CA2 (0.65) CA2KMT2ACA1CA9IDO1
Ammonia Solution, Strong SCHEMBL28512991 0.83 CA2 (0.64) CA2KMT2ACA1CA9IDO1
SCHEMBL16755999 0.83 CA2 (0.69) CA2KMT2ACA1CA9IDO1
Ammonia Solution, Strong SCHEMBL28724322 0.82 CA2 (0.63) CA2KMT2ACA1CA9IDO1
Ammonia Solution, Strong SCHEMBL28783255 0.82 KMT2A (0.67) CA2KMT2ACA1CA9IDO1
Ammonia Solution, Strong SCHEMBL28355326 0.82 CA2 (0.63) CA2KMT2ACA1CA9AGXT
Ammonia Solution, Strong SCHEMBL28808949 0.82 CA2 (0.63) CA2KMT2ACA1CA9IDO1
SCHEMBL778365 0.81 CA2 (0.67) CA2KMT2ACA1CA9IDO1
SCHEMBL777315 0.81 CA2 (0.66) CA2KMT2ACA1CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112321469-B Synthetic method of dibenzyl sulfide 成都理工大学 2022-07-12 CN claimed
CN-115724884-A Synthesis method of benzylphosphine oxide compound 海南大学 2023-03-03 CN disclosed
CN-112321469-B Synthetic method of dibenzyl sulfide 成都理工大学 2022-07-12 CN disclosed
CN-114195610-A Synthetic method of E-type internal olefin compound 海南大学 2022-03-18 CN disclosed
CN-112321469-A Synthetic method of dibenzyl sulfide 成都理工大学 2021-02-05 CN disclosed