Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15821832 | 0.98 | MAP4K4 (0.47) | MAP4K4OPRM1ALDH1A1NPC1RAB9A | |
| SCHEMBL876741 | 0.97 | MAP4K4 (0.45) | MAP4K4OPRM1ALDH1A1NPC1RAB9A | |
| SCHEMBL29574467 | 0.93 | OPRM1 (0.42) | MAP4K4OPRM1TNF | |
| SCHEMBL350982 | 0.93 | OPRM1 (0.42) | MAP4K4OPRM1TNF | |
| SCHEMBL15129658 | 0.85 | OPRM1 (0.38) | MAP4K4OPRM1TNFSLC6A4SLC6A3 | |
| SCHEMBL5309575 | 0.85 | OPRM1 (0.38) | MAP4K4OPRM1TNF | |
| SCHEMBL15129340 | 0.84 | PDE4A (0.41) | MAP4K4OPRM1NPC1RAB9AMEN1 | |
| SCHEMBL31014508 | 0.81 | OPRM1 (0.33) | MAP4K4OPRM1NPC1RAB9ATNF | |
| SCHEMBL1141603 | 0.79 | MAP4K4 (0.45) | MAP4K4OPRM1ALDH1A1NPC1RAB9A | |
| SCHEMBL25512254 | 0.79 | MAP4K4 (0.42) | MAP4K4OPRM1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026090477-A1 | HELICASE INHIBITORS AND USES THEREOF | KIMIA THERAPEUTICS, INC. (US) | 2026-04-30 | — | — | WO | disclosed |
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113061098-A | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-07-02 | — | — | CN | disclosed |