Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.66 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.66 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.60 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 15/20 | 0.54 |
| ▸ | F13A1 | P00488 | 2/20 | 0.53 |
| ▸ | TGM1 | P22735 | 2/20 | 0.53 |
| ▸ | TGM6 | O95932 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 2/20 | 0.53 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2859559 | 1.00 | DPP4 (0.66) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL21009799 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL19707914 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL10074998 | 0.86 | DPP4 (0.53) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL10078264 | 0.86 | DPP4 (0.53) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL6766563 | 0.86 | ITGB3 (0.65) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL13598866 | 0.86 | ITGB3 (0.65) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL10074729 | 0.85 | DPP8 (0.55) | DPP4DPP8DPP9DPP7ITGB3 | |
| SCHEMBL28290510 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BTGM2F13A1TGM1 | |
| SCHEMBL28290512 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BTGM2F13A1TGM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790725-B2 | Thiazolidine derivatives and medicinal use thereof | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20070259880-A1 | THIAZOLIDINE DERIVATIVES AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORPORATION (JP) | 2007-11-08 | — | — | US | disclosed |
| US-20040259883-A1 | Thiazolidine derivative and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1426366-A1 | THIAZOLIDINE DERIVATIVE AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2004-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259880-A1 | THIAZOLIDINE DERIVATIVES AND MEDICINAL USE THEREOF | DPP4, DPP7, DPP3 | DPP4 1/4885DPP8 5/4885DPP9 4/4885 |
| US-20040259883-A1 | Thiazolidine derivative and medicinal use thereof | DPP4, DPP7, DPP3 | DPP4 1/4885DPP8 5/4885DPP9 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.