Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ALPI | P09923 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PAM | P19021 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.32 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447152 | 0.74 | KMT2A (0.38) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL5880589 | 0.72 | CA12 (0.41) | ALPLALPIKMT2AMEN1LMNA | |
| SCHEMBL28591321 | 0.72 | CA12 (0.39) | KMT2AMEN1LMNAALDH1A1KDM4E | |
| SCHEMBL6431070 | 0.68 | CA12 (0.42) | ALPLALPIKMT2AMEN1LMNA | |
| SCHEMBL5782636 | 0.68 | HSD17B10 (0.41) | LMNAMAPTALDH1A1KDM4ECA12 | |
| SCHEMBL28241854 | 0.66 | KDM4E (0.39) | ALPLALPIKMT2AMEN1LMNA | |
| SCHEMBL11695481 | 0.65 | CA12 (0.41) | ALPLALPIKMT2AMEN1LMNA | |
| SCHEMBL18953560 | 0.65 | CA12 (0.41) | ALPLALPIKMT2AMEN1LMNA | |
| SCHEMBL5624611 | 0.62 | L3MBTL1 (0.38) | ALPLALPIKMT2AMEN1LMNA | |
| SCHEMBL6555497 | 0.62 | CA12 (0.38) | ALPLALPIKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121470-A | Preparation method of benzothiadiazine-1, 1-dioxide compound | 天津理工大学 | 2021-07-16 | — | — | CN | disclosed |