Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31174791 | 1.00 | EPHX2 (0.54) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL11477159 | 0.84 | EPHX2 (0.63) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29935788 | 0.83 | KAT6A (0.44) | EPHX2NPC1RAB9AFGFR1ALDH1A1 | |
| SCHEMBL11901262 | 0.81 | ALDH1A1 (0.49) | EPHX2ALDH1A1POLBL3MBTL1NTRK1 | |
| SCHEMBL24856259 | 0.79 | NTRK1 (0.57) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21863392 | 0.77 | EPHX2 (0.57) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21849159 | 0.76 | EPHX2 (0.64) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL3606688 | 0.76 | GAA (0.55) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22900555 | 0.75 | EPHX2 (0.43) | EPHX2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21816235 | 0.75 | MEN1 (0.75) | EPHX2NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | claimed |
| CN-113164458-A | Monoacylglycerol lipase modulators | 詹森药业有限公司 | 2021-07-23 | — | — | CN | disclosed |