Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473008 | 1.00 | USP2 (0.49) | USP2RAD52OPRD1ALDH1A1TSHR | |
| SCHEMBL22801996 | 0.88 | MAPT (0.46) | USP2RAD52OPRD1ALDH1A1TSHR | |
| SCHEMBL22801980 | 0.88 | MAPT (0.46) | USP2RAD52OPRD1ALDH1A1TSHR | |
| SCHEMBL3168784 | 0.87 | RAD52 (0.44) | USP2RAD52ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5631357 | 0.87 | RAD52 (0.44) | USP2RAD52OPRD1ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL2925849 | 0.85 | RAD52 (0.46) | USP2RAD52ALDH1A1TSHRHSD17B10 | |
| SCHEMBL5742221 | 0.84 | OPRD1 (0.46) | RAD52OPRD1ALDH1A1HSD17B10MAPT | |
| SCHEMBL18889530 | 0.82 | HSD17B3 (0.43) | RAD52ALDH1A1ADRB1MAPTKMT2A | |
| SCHEMBL19617168 | 0.81 | HTT (0.49) | RAD52ALDH1A1TSHRTDP1POLB | |
| SCHEMBL22411659 | 0.81 | RAD52 (0.49) | RAD52ALDH1A1ADRB1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |