Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decarboxylated Derivative SCHEMBL28037171 | 0.97 | CYP2D6 (0.53) | CYP2D6PLGPLATLMNAADH1B | |
| Formic Acid SCHEMBL27889793 | 0.95 | — | — | |
| Decarboxylated Derivative SCHEMBL27363844 | 0.84 | CYP2D6 (0.50) | CYP2D6PLGPLATLMNAADH1B | |
| SCHEMBL27810 | 0.83 | — | — | |
| Bicarbonate SCHEMBL15519847 | 0.81 | CYP2D6 (0.63) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL13893972 | 0.80 | CYP2D6 (0.54) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL18102722 | 0.80 | CYP2D6 (0.54) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL3536114 | 0.80 | CYP2D6 (0.54) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL22078896 | 0.80 | CYP2D6 (0.54) | CYP2D6PLGPLATLMNANCF1 | |
| SCHEMBL14417464 | 0.80 | CYP2D6 (0.54) | CYP2D6PLGPLATLMNANCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053742-B | Novel tricyclic compounds | ABBVIE 公司 | 2021-06-15 | — | — | CN | disclosed |