Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 4/20 | 0.59 |
| ▸ | MAOB | P27338 | 4/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.46 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26924063 | 0.89 | CYP2D6 (0.78) | CYP2D6MAOAMAOBACHESLC6A4 | |
| SCHEMBL17502355 | 0.86 | MAOA (0.78) | CYP2D6MAOAMAOBACHEHASPIN | |
| Trimethylammonium SCHEMBL28596346 | 0.85 | CYP2D6 (0.63) | CYP2D6MAOAMAOBACHESLC6A2 | |
| SCHEMBL17102952 | 0.85 | MAOA (0.68) | CYP2D6MAOAMAOBACHEHASPIN | |
| SCHEMBL17502362 | 0.84 | MAOA (0.81) | CYP2D6MAOAMAOBACHEHASPIN | |
| SCHEMBL17502364 | 0.84 | MAOA (0.81) | CYP2D6MAOAMAOBACHEHASPIN | |
| SCHEMBL15848971 | 0.84 | CYP2D6 (0.60) | CYP2D6MAOAMAOBACHESLC6A4 | |
| SCHEMBL17502374 | 0.84 | MAOA (0.81) | CYP2D6MAOAMAOBACHEHASPIN | |
| SCHEMBL17517489 | 0.84 | MAOA (0.81) | CYP2D6MAOAMAOBACHEHASPIN | |
| SCHEMBL8162588 | 0.83 | MAOA (0.70) | CYP2D6MAOAMAOBACHEHASPIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113416187-B | Alkylamine harmine derivatives for promoting bone growth | 奥斯菲治疗有限公司 | 2024-07-19 | — | — | CN | disclosed |
| CN-113416187-A | Alkylamine peganine derivatives for promoting bone growth | 奥斯特克有限公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-105120863-B | Alkylamine peganine derivatives for promoting bone growth | 奥斯特克有限公司 | 2021-06-04 | — | — | CN | disclosed |