SCHEMBL28596708

SCHEMBL28596708

Cc1ccc(-c2ccc3oc4ccc(-c5c[c]ccc5)cc4c3c2)c(C)n1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK9 P50750 1/20 0.35
DYRK1A Q13627 1/20 0.35
DYRK2 Q92630 1/20 0.35
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
GRIA2 P42262 1/20 0.32
TGFBR1 P36897 1/20 0.31
PIM1 P11309 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
PIM3 Q86V86 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
PLA2G2A P14555 1/20 0.31
PLA2G4A P47712 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28595085 0.84 DYRK1A (0.38) CDK9DYRK1ADYRK2GAAL3MBTL1
SCHEMBL28586225 0.84 PRMT5 (0.38) CDK9DYRK1ADYRK2GAAL3MBTL1
SCHEMBL6292114 0.79 CYP1A2 (0.35) GRIA2RAB9A
SCHEMBL28603940 0.78 HAVCR2 (0.36) CDK9DYRK1APIM1ALDH1A1MAPT
SCHEMBL28608527 0.78 TGFBR1 (0.33) CDK9DYRK1ADYRK2GAAL3MBTL1
SCHEMBL15987666 0.77 MAPT (0.46) PLA2G2APLA2G4AALDH1A1MAPTKDM4E
SCHEMBL28598897 0.76 CLK4 (0.37) CDK9DYRK1ADYRK2PLA2G2APLA2G4A
SCHEMBL28917471 0.76 DYRK1A (0.43) DYRK1APLA2G2APLA2G4AMAPT
SCHEMBL28592516 0.75 ATM (0.37) CDK9DYRK1ADYRK2PIM1PIM2
SCHEMBL28592108 0.74 CYP2A6 (0.40) CDK9DYRK1ADYRK2GAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed